Analog Devices Inc. ADuCM355 Precision Analog Microcontroller

Analog Devices ADuCM355 Precision Analog Microcontroller (MCU) offers an on-chip system that controls and measures electrochemical sensors and biosensors. This MCU comes with a chemical sensor interface and facilitates a mixed signal MCU which is based on Arm® Cortex™-M3 processor. The ADuCM355 Analog MCU is capable of current, voltage, and impedance measurements and features a 16-bit, 400kSPS ADC with ultralow leakage switch matrix and input MUX. This MCU operates at 2.8V to 3.6V supply range and -40°C to 85°C ambient temperature range. The ADuCM355 Analog Microcontroller is available in 6mm x 5mm, 72-lead LGA package. Typical applications include gas detection, food quality, blood glucose meters, and bioimpedance measurements.


  • Analog input/output:
    • Voltage, current, and impedance measurement capability
    • Internal and external current and voltage channels
    • Ultralow leakage switch matrix and input MUX
    • Input buffers PGA
  • Voltage DACs:
    • 2 dual output voltage DACs
    • 2 bias potentiostat and TIA amplifiers
    • High-speed TIA for impedance measurements
    • The programmable gain amplifier on the output
  • Amplifiers, accelerators, and references:
    • Suitable for potentiostat bias in electrochemical sensing
    • Digital waveform generator (refer to the ADuCM355 hardware reference manual)
    • DFT and digital filters
  • Hardware Cyclic Redundancy Check (CRC) with programmable polynomial generator
  • Read and write protection of user flash


  • Gas detection
  • Food quality
  • Environmental sensing (air, water, and soil)
  • Blood glucose meters
  • Life sciences and biosensing analysis
  • Bioimpedance measurements
  • General amperometry, voltammetry, and impedance spectroscopy functions


  • Analog input/output:
    • 16-bit, 400kSPS ADC
  • Voltage DACs:
    • 0.2V to 2.4V output range (±2.2V voltage potential to sensor) for 12-bit outputs
    • 1μA per amplifier
    • 1 high-speed 12-bit voltage DAC
    • -607mV to 607mV output range to the sensor
  • 2.8V to 3.6V supply and active measurement range
  • 6mm x 5mm dimensions with 72-lead LGA package
  • -40°C to 85°C ambient operating temperature range

Block Diagram

Block Diagram - Analog Devices Inc. ADuCM355 Precision Analog Microcontroller

Outline Dimensions

Mechanical Drawing - Analog Devices Inc. ADuCM355 Precision Analog Microcontroller

Additional Resources

Liquid Measurements – From Water to Blood

This article concentrates on fluid measurements with medical uses and thereby describes the individual applications as well as the versatility of impedance measurements. 

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The Technical Challenges of Electrochemical Gas Sensing

Developing gas sensing systems of the future presents many challenges to overcome. They must accurately measure much lower concentrations, be more selective toward the target gases, operate for longer durations from battery power and provide consistent performance over longer periods of time while always maintaining safe and reliable operation. But where to start?

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Published: 2019-05-20 | Updated: 2023-01-13